Meta-analysis Shows Post-op Opioid Consumption Reduction Possible With Right Pain Control Approach

A comprehensive review of multiple studies evaluated the effects of post-op nonopioid adjunct analgesia on postoperative opioid consumption and pain control in patients undergoing knee arthroscopy.​​ Read the summary.

Post-op nonopioid pharmacotherapy, saphenous nerve blocks, and cryotherapy for patients undergoing knee arthroscopy significantly reduce opioid consumption and pain scores when compared to placebo at 24 hours postoperatively. 

Both preoperative patient education and postoperative cryotherapy reduced postoperative opioid consumption.

Following meta-analysis of more than twenty independent studies, researchers identified these key results:

  • Nonopioid pain medications demonstrated a reduction in cumulative postoperative oral morphine equivalent (OME) consumption by 11.8 mg at 24 hrs compared to placebo
  • Postoperative nonopioid pain medications significantly reduced cumulative postoperative morphine equivalent (OME) consumption by 9.7 mg at 24 hrs compared to placebo
  • Both preoperative patient education and postoperative cryotherapy reduced postoperative opioid consumption.

Access the full case study: Perioperative nonopioid analgesia reduces postoperative opioid consumption in knee arthroscopy: a systematic review and meta-analysis

Cryotherapy Study Shows Pain Management Gains with Compression

A study originally published in The Journal of Knee Surgery looks at the efficacy of cryotherapy combined with compression in ACL repair cases, versus standard cryotherapy alone. Read the summary.

Patient Education Materials Study Shows Gap in Recommended Reading Levels

A recent study looked at the content and quality of online patient education material related to postoperative opioid use in pain management. Read the results in the summary.

Changing Patient Behavior in Disposal of Excess Opioids

A surgical center partnered with a nonprofit agency to study the behavior of patients in disposing of excess opioids prescribed to them following outpatient surgery. Read the summary.

Are Opioids Always Necessary? This Post-op Protocol Study Says Maybe Not.

A recent study (2021) assessed the efficacy of nonopioid pain protocols versus opioid control in mitigating postoperative pain following knee surgery. Read the surprising results in the summary.

Opioid Education’s Impact 2 Years Post Op

Rothman Institute studied the impact of preoperative opioid use education on opioid consumption at a 2 year follow up interval with surgery patients. The study received a 2018 Neer Award.…

Study Finds Optional Opioid Refills Leads to Safer Communities

A recent study examined the impact of prescription instructions on the consumption of opioids by patients following knee surgery. Read the results in the summary.

Opioid Education Study Proves Knowledge is Power

Researchers assessed the relationship between preoperative opioid use education and consumption by surgical patients. Their findings were published in JAMA. Read the summary.


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